유전자 치료 과녁 발견과 약물 개발 과정에서 어떻게 유전자 조각을 목적지 조직 기관에 효율적이고 정확하게 전달하며 기체 면역, 탈과효과 등의 부작용을 일으키지 않는 것은 현재 공략해야 할 큰 기술적 난점이다.... Read More ›
색소성 망막염 GTP 효소조절인자(RPGR) 유전자의 돌연변이는 X연쇄 색소성 망막염(XLRP)과 연관돼 전체 색소성 망막염(RP)의 10~20%를 차지하는 가장 심각한 형태 중 하나다.... Read More ›
CASK, APBA1, and STXBP1 collaborate during insulin secretion
Mol Cell Endocrinol. DOI: 10.1016/j.mce.2020.111076 (2020)
Lineage Tracing of Cells Expressing the Ciliary Gene IFT140 During Bone Development
Developmental Dynamics. DOI: 10.1002/dvdy.266 (2020)
Shrm4 contributes to autophagy inhibition and neuroprotection following ischemic stroke by mediating GABA B re...
FASEB J. DOI: 10.1096/fj.202000458RR (2020)
Neuraminidase-1 promotes heart failure after ischemia/reperfusion injury by affecting cardiomyocytes and invad...
Basic Res Cardiol. DOI: 10.1007/s00395-020-00821-z (2020)
Suppression of DDX39B sensitizes ovarian cancer cells to DNA-damaging chemotherapeutic agents via destabilizin...
Oncogene DOI: 10.1038/s41388-020-01482-x (2020)
The piRNA CHAPIR regulates cardiac hypertrophy by controlling METTL3-dependent N 6-methyladenosine methylation...
Nat Cell Biol. DOI: 10.1038/s41556-020-0576-y (2020)
“Using Cyagen’s CRISPR-generated constitutive knockout mice has greatly facilitated our understanding the biology in IL-1 family of 1...—— Charles A. Dinarello, University of Colorado Denver - Anschutz Medical Campus
“Cyagen made two reporter knock-in mice (i.e. MLC-2v-tdTomato and Nppa-tagBFP) which were used in my recent publications. Both reporters we...—— Young-Jae Nam, Vanderbilt University Medical Center
"Our lab has been using Cyagen’s transient transgenic mouse embryo LacZ service to test candidate sequences for enhancer activity for over five ...—— Nadav Ahituv, University of California, San Francisco
"We are very pleased with the state-of-the-art professional transgenic services provided by Cyagen for our study published recently in Nature. We cont...—— Stanford University
“Among several commercial services who have claimed to be specialized to generate mouse models with genetic modifications, I recognize that Cyag...—— Korea Brain Research Institute (KBRI)
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