녹아웃(KO) 마우스 | Cyagen Korea

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“Among several commercial services who have claimed to be specialized to generate mouse models with genetic modifications, I recognize that Cyagen is one of the best. We are looking forward to having more cooperation with them.”

Korea Brain Research Institute (KBRI)

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Genetic Background: NOD

Color: Albino

Genetics:
Coat Color Loci: Tyrc

Strain Description:

  •    The SCID mutation was introduced on the basis of the background strain of non-obese diabetic (NOD) mice
  •   Congenital T and B lymphocyte immunodeficiency.
  •   Due to the NOD background, the activity of NK cells is decreased.
  •   Does not develop diabetes.

Phenotype Information and Application:

  •    Multiple unique multiple immunodeficiencies provide an excellent system for the reconstruction of human hematopoietic cells, and it is an important model for HIV-1 (human immunodeficiency virus 1) research and gene therapy.
  •   An important tool for tumor research that can increase the incidence of tumors, especially lymphoma and thymoma.
  •   In the case of transplantation of fatal thymic lymphoma, the life span is shortened (about 8-9 months).

Health Standard SPF

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