About 50 years ago, scientists made the surprising discovery that some diseases, such as mad cow disease and Creutzfeldt-Jakob disease are transmitted by...
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Tobacco use represents a major worldwide health problem. Around one fifth of the world's population regularly smokes tobacco and nearly half of these people...
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Blindness is a major public health problem. Nearly 40 million people worldwide are functionally blind, while over 250 million people suffer from visual...
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In an era of designer mice and complex multi-component DNA constructs, it is difficult to imagine that there was a time (not so long ago) when biologists lacked...
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Virus transduction is a common method used to introduce new genetic material into cells. Since the first use of a viral vector on mammalian cells in the 1970's...
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Superheroes are a pop culture phenomenon. Their amazing abilities entertain and inspire us, but hardly seem attainable in the real world. However, superpowers...
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HIV infection affects more than 35 million people worldwide. Over the past three decades, progress has been made in HIV treatment, mostly through the use of...
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For more than a century, rodents have played a pivotal role in biomedical research, and provided experimental systems for investigating mammalian biology...
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Animal models play a vital role in modern biomedical research. In particular, mouse and rats are profoundly important. However, mice and rats are imperfect...
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The gold standard for genetically engineering mouse models is ES-cell based homologous recombination. However, this approach is very time-consuming...
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